Legal Safe Peptide Hormones Bodybuilding CJC-1295 Acetate / DAC Growth Hormone - Product

Other Specification :  Legal Safe Peptide Hormones Bodybuilding CJC-1295 Acetate / DAC Growth Hormone Quick Detail: CJC-1295 Acetate With DAC Growth Hormone Releasing Hormone (GHRH) Specification:2mg/10vials/kit Molecular Formula : C165H269N47O46 Molecular Weight : 3647.15 CAS No. : 863288-34-0 Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys(maleimido) Description: CJC-1295 Is A Tetrasubstituted 30-amino Acid Peptide Hormone, Primarily Functioning As A Growth Hormone Releasing Hormone (GHRH) Analog. One Of The Advantages Of CJC-1295 Over Traditional GHRH Or RHGH Is Its Ability To Bioconjugate With Serum Albumin, Thus Increasing Its Half-life And Therapeutic Window. It Accomplishes This By Using Protecting Groups Around The Amino Acids Of GHRH Typically Susceptible To Enzymatic Degradation. Clinical Research Was First Conducted For CJC-1295 During The Mid-2000s. The Objective Of The Peptide Was To Treat Visceral Fat Deposits In Obese AIDS Patients, As Increased Levels Of Exogenous HgH Are Presumed To Increase Lipolysis (fat Loss). The Clinical Research Was Ultimately Successful For Most Research Subjects. CJC-1295 Is A Tetrasubstituted Peptide Analogue Of GHRH With D-Ala, Gln, Ala, And Leu Substitutions At Positions 2, 8, 15, And 27 Respectively. These Substitutions Create A Much More Stable Peptide With The Substitution At Position 2 To Prevent DPP-IV Cleavage, Position 8 To Reduce Asparagine Rearrangement Or Amide Hydrolysis To Aspartic Acid, Position 15 To Enhance Bioactivity, And Position 27 To Prevent Methionine Oxidation. These Substitutions Are Key In Increasing The Overall Half Life Of CJC-1295 But There Lies An Even Greater Reason As To Why The Half Life Has Been Extended From ~7 Minutes To Greater Than 7 Days! Bioconj

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