Emulsifier Pharmaceutical Excipients , Vitamin E TPGS Solubilizing Agent - Product

Other Specification : Vitamin E TPGS , Emulsifyer , Solubilizing Agent Introduction D--Tocopheryl Polyethylene Glycol 1000 Succinate (simply TPGS Or Vitamin E TPGS) Is Formed By The Esterification Of Vitamin E Succinate With Polyethylene Glycol 1000. As Novel Nonionic Surfactant, It Exhibits Amphipathic Properties And Can Form Stable Micelles In Aqueous Vehicles At Concentration As Low As 0.02 Wt%. Application It Has Been Widely Investigated For Its Emulsifying, Dispersing, Gelling, And Solubilizing Effects On Poorly Water-soluble Drugs. It Can Also Act As A P-glycoprotein (P-gp) Inhibitor And Has Been Served As An Excipient For Overcoming Multidrug Resistance (MDR) And For Increasing The Oral Bioavailability Of Many Anticancer Drugs. Since TPGS Has Been Approved By FDA As A Safe Pharmaceutic Adjuvant, Many TPGS-based Drug Delivery Systems (DDS) Have Been Developed. Specification - - - - CAS NO. | 9002-96-4 | Item | Specification | Appearance | White To Brownish Waxy Solid | Purity By HPLC | Not Less Than 99.5% | Odor | Nearly Odorless | Acidity[mg KOH/g] | Not More Than 1.5 | Content Of VE | Not Less Than 250mg/g | Solubility In Water | 20g Sample Can Be Dissolved In 80ml Boiling Water | - - - - Other Information Shelf Life :at Least 2 Years Sealed In Original Sealed Container Country Of Origin : China Standard : In House Standard Package Size :25kgs/drum Storage : Keep Tightly Closed In A Dry And Cool Place. Do Not Expose To Excessive Heat Or Cold

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